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- Short: ABaCUS 0.48 for AMIGA
- Type: misc/sci
- Uploader: peru@maya.dei.unipd.it (Steve Peruzzi)
- Author: peru@maya.dei.unipd.it (Steve Peruzzi)
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- WHAT IS ABACUS?
-
- ABaCUS is a no-frills program developed to investigate the significance of
- the putative correspondence between exons and units of protein structure.
- This type of analysis takes the form of an attempt to eliminate the
- reference hypothesis (sometimes called a "null" hypothesis) that no
- correspondence exists. A reference hypothesis in this case consists of a
- reference model for random gene structures, and a scoring rule for
- quantifying correspondences.
-
- ABaCUS creates and reads files containing observed data supplied by the
- user, then uses this information to generate reference genes according to
- one of several available models. The observed and reference genes are then
- scored according to a correspondence rule designated by the user, and the
- scores are compared in order to determine whether the reference hypothesis
- (i.e., no correspondence) can be rejected.
-
- This program may be useful in your research if you are studying the origin
- and evolution of intron-containing genes.
-
- This is the porting for AMIGA, and has been compiled with SAS-C V6.51.
- To run simply open a SHELL and type ABACUS, for infos on using ABACUS
- read the manual ABACUS.HLP. This archive includes also a PDB file for
- a tutorial: a cytochrome C from rice embryos (read the manual).
-
- Thanx to
-
- Dr. Arlin Stoltzfus and Dr. David Spencer
- Canadian Institute for Advanced Research, Dalhousie University
-
- for this excellent tool.
-
- Steve Peruzzi
- peru@maya.dei.unipd.it
- University of Padua, ITALY
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